What is a Inunction?

What is a Inunction?

Medical Definition of inunction 1 : an act of applying an oil or ointment specifically : the rubbing of an ointment into the skin for therapeutic purposes. 2 : ointment, unguent.

What does it mean when a drug is absorbed?

Drug absorption is the movement of a drug into the bloodstream after administration. (See also Introduction to Administration and Kinetics of Drugs.) Absorption affects bioavailability—how quickly and how much of a drug reaches its intended target (site) of action.

What drugs are absorbed?

The human stomach is capable of absorbing most acidic drugs and the very weakly basic drugs. Salicylic acid, aspirin, thiopental, secobarbital and antipyrine, which are undissociated in the acidic gastric contents, were readily absorbed.

What is the meaning of insufflation?

Insufflation (Latin: insufflare, lit. ‘to blow into’) is the act of blowing something (such as a gas, powder, or vapor) into a body cavity. Insufflation has many medical uses, most notably as a route of administration for various drugs.

Which drug form is most rapidly absorbed?

Because the cell membrane is lipoid, lipid-soluble drugs diffuse most rapidly. Small molecules tend to penetrate membranes more rapidly than larger ones. Most drugs are weak organic acids or bases, existing in un-ionized and ionized forms in an aqueous environment.

How is insufflation done?

Laparoscopic surgery involves insufflation of a gas (usually carbon dioxide) into the peritoneal cavity producing a pneumoperitoneum. This causes an increase in intra-abdominal pressure (IAP). Carbon dioxide is insufflated into the peritoneal cavity at a rate of 4–6 litre min−1 to a pressure of 10–20 mm Hg.

What is insufflation and Exsufflation?

Mechanical insufflation-exsufflation is a therapy in which the device (the CoughAssist In-Exsufflator is the only currently marketed insufflation-exsufflation device) gradually inflates the lungs (insufflation), followed by an immediate and abrupt change to negative pressure, which produces a rapid exhalation ( …

What is the meaning of instillation?

Medical Definition of instillation 1 : an act of instilling : introduction by instilling repeated instillation of penicillin. 2 : something that is instilled or designed for instillation silver instillation for use in the eyes of the newborn.

Which coating is thin and dissolve rapidly?

Explanation: Film coating is thin and dissolves rapidly and thus don’t affect drug absorption. Sugar coat is tough and takes a longer time than film coating to dissolve.

Which salt of basic drug has more bioavailability?

Prasugrel is available as a hydrochloride salt, which was found to offer better absorption at higher gastric pH, when compared with the free base form.