Is clindamycin soluble in water?

Is clindamycin soluble in water?

Clindamycin phosphate is soluble in water. This solubility is pH dependent: at pH 7 the solubility is between 200 and 300 mg/mL, whereas at pH 4 it is 25 mg/mL. Clindamycin phosphate infusion is administered over 10–45 minutes, depending on the dose.

Does clindamycin solution have alcohol?

For patients using the topical solution form of clindamycin: After washing or shaving, it is best to wait 30 minutes before applying this medicine. The alcohol in it may irritate freshly washed or shaved skin. This medicine contains alcohol and is flammable.

What is clindamycin solution?

CLINDAMYCIN (KLIN da MYE sin) is a lincosamide antibiotic. It is used on the skin to stop the growth of certain bacteria that cause acne.

Is clindamycin polar?

Clindamycin is a Lincosamide Antibacterial. The physiologic effect of clindamycin is by means of Decreased Sebaceous Gland Activity….3.1Computed Properties.

Is clindamycin gel or solution better?

Conclusion: Clindamycin gel, 1% once a day showed a similar efficacy profile than clindamycin solution, 1% twice a day in the treatment of mild to moderate acne vulgaris and was significantly superior to its vehicle and has a better safety profile compared to that of clindamycin solution 1%.

How long does clindamycin stay in the body?

After oral administration of clindamycin hydrochloride, elimination half-life is increased to approximately 4.0 hours (range 3.4-5.1 h) in the elderly compared to 3.2 hours (range 2.1 – 4.2 h) in younger adults.

Do you put clindamycin all over your face?

Use only a pea-sized amount of clindamycin and tretinoin topical. Apply to your entire face every night at bedtime. Do not wash your face more than 3 times daily while using this medication. Washing more often or scrubbing your face when you wash it can make your acne worse.