Can you be allergic to carboplatin?

Can you be allergic to carboplatin?

For women with recurrent ovarian cancer, re-treatment with carboplatin is frequently recommended. However, carboplatin re-treatment can result in an allergic or allergic-like reaction called a hypersensitivity reaction.

When does a hypersensitivity reaction to carboplatin typically occur?

Hypersensitivity reactions always occurred after administration of the first 4 intravenous courses of carboplatin; 4, 19, 4, and 5 reactions occurred at the 5th, 6th, 7th, and 8th courses, respectively.

What is carboplatin desensitization?

Carboplatin desensitization prevents life-threatening HSRs and promotes the successful completion of planned chemotherapy. Methods: Since January 2010, carboplatin desensitization was performed at our institution.

What class of chemotherapy is carboplatin?

Drug type: Carboplatin is an anticancer drug (“antineoplastic” or “cytotoxic”) chemotherapy drug. Carboplatin is classified as an “alkylating agent.”

What is an expected side effect of carboplatin?

Stomach pain, body aches/pain, diarrhea, constipation, weakness, nausea, and vomiting may occur. Nausea and vomiting can be severe in some patients but usually go away within 24 hours of treatment. Drug therapy may be needed to prevent or relieve nausea and vomiting.

Is carboplatin effective on its own?

Any effect carboplatin has is usually mild and will get better by itself.

How do you reduce the side effects of carboplatin?

Changes in diet such as eating several small meals or limiting activity may help lessen some of these effects. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Temporary hair loss may occur. Normal hair growth should return after treatment has ended.

What are the common side effects of carboplatin?

Stomach pain, body aches/pain, diarrhea, constipation, weakness, nausea, and vomiting may occur. Nausea and vomiting can be severe in some patients but usually go away within 24 hours of treatment.

What is chemo desensitization?

Desensitization protocols are available to treat hypersensitivity reactions to most chemotherapy agents including taxenes, platinums, doxorubicin, monoclonal antibodies and others, by gradual re-introduction of small amounts of drug antigens up to full therapeutic doses.

What are the side effects of carboplatin chemotherapy?

How many cycles of carboplatin can you have?

When you have carboplatin You might have carboplatin every 3 to 4 weeks. Each 3 or 4 week period is a cycle of treatment. You might have between 4 to 6 cycles.

Will I lose my hair on carboplatin?

Your hair may get thinner. But you are unlikely to lose all the hair from your head. Hair loss usually starts after your first or second treatment. It is almost always temporary, and your hair will usually grow back after treatment finishes.

How does carboplatin make you feel?

You may get pain or discomfort in your tummy (abdomen). You may also feel bloated or have indigestion or wind. Your doctor can prescribe drugs to help improve these symptoms. Tell them if the pain does not improve or gets worse.

Does rapid drug desensitization to chemotherapy affect survival outcomes?

Conclusions: Survival outcomes of oxaliplatin-hypersensitive patients who received oxaliplatin via RDD did not differ significantly from those of control patients who received oxaliplatin via standard administration.

How quickly does carboplatin work?

How long does treatment take? Each dose, or cycle, of carboplatin takes 15 minutes to an hour. It may take longer if you are having carboplatin with other drugs. You’ll usually have one cycle of carboplatin every 21–28 days.

What is the success rate of carboplatin?

The 5-year overall survival rates were 66% in cisplatin/vinorelbine group, 55% in carboplatin/vinorelbine group and 70% in cisplatin/vinorelbine/carboplatin/vinorelbine group ( p = 0, 95).