Can you take Prograf while pregnant?

Can you take Prograf while pregnant?

Use is not recommended. US FDA pregnancy category: Not assigned. Risk Summary: This drug can cause fetal harm when administered to a pregnant woman. Infants exposed in utero are at a risk of prematurity, birth defects/congenital anomalies, low birth weight, and fetal distress.

Can tacrolimus cause birth defects?

No major congenital malformations were reported in the 9 infants born to women taking tacrolimus. A 2008 abstract based on data from the NTPR reported 3 infants (4.2%) with birth defects among 102 pregnancies in kidney transplant recipients treated with tacrolimus (without mycophenolate mofetil) during pregnancy.

Is topical tacrolimus safe in pregnancy?

The use of systemically administered tacrolimus during pregnancy has been associated with neonatal hyperkalemia and renal dysfunction. PROTOPIC Ointment should be used during pregnancy only if the potential benefit to the mother justifies a potential risk to the fetus.

How much alcohol can a pregnant woman drink without risking harm to her unborn baby?

Although no amount of alcohol is considered safe during pregnancy, it is known that drinking 8 or more drinks a week or 5 or more drinks in one day will affect an unborn baby. At this time, the possible effects of lesser amounts of alcohol on an unborn baby are not known with certainty.

What happens when your tacrolimus level is too high?

Tacrolimus can cause kidney damage (nephrotoxicity), especially in high doses. Measuring levels in people who have had a kidney transplant may help to distinguish between kidney damage due to rejection (because drug level is low) and kidney damage due to tacrolimus toxicity (drug level is high).

What happens if I miss my Prograf?

If you miss a dose of your medicine at the scheduled time, don’t panic. Take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and return to your regular medicine schedule.

What are anti rejection drugs?

Antirejection (Immunosuppressant) Medications

• Prednisone.
• Tacrolimus (Prograf)
• Cyclosporine (Neoral)
• Mycophenolate Mofetil (CellCept)
• Imuran (Azathioprine)
• Rapamune (Rapamycin, Sirolimus)

  Is topical tacrolimus safe during pregnancy?

  Tacrolimus topical Pregnancy Warnings US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

  Does tacrolimus cause birth defects?

  There have been reports of case series of human pregnancies with tacrolimus exposure (approximately 200 pregnancies) in post-transplant patients. Most authors reported favourable pregnancy outcomes, with no evidence of increased risk of congenital malformations.

  Why is my eczema so bad during pregnancy?

  Hormone fluctuations may lead to an eczema flare-up during pregnancy, but keeping your skin moisturized can help tame symptoms. It’s not only your body that changes during pregnancy — your skin can go through a roller coaster of changes, too.