Does Xyrem help you sleep?

Does Xyrem help you sleep?

Does Xyrem help you sleep?

XYREM is taken at night to reduce both excessive daytime sleepiness (EDS) in narcolepsy and cataplexy in narcolepsy during the day. XYREM can cause sleep very quickly. Some people fall asleep within 5 minutes, and most people fall asleep within about 15 minutes.

Do narcoleptics sleep well at night?

Do narcoleptics sleep well at night? About half of people with narcolepsy have trouble sleeping through the night. You may wake up frequently (fragmented sleep) and have difficulty falling back to sleep.

How long does it take for someone with narcolepsy to fall asleep?

REM sleep is typically when most dreaming happens. REM sleep can occur at any time of the day in people with narcolepsy. People with narcolepsy often transition quickly to REM sleep, usually within 15 minutes of falling asleep.

How does narcolepsy affect nighttime sleep?

Nighttime sleep in patients with narcolepsy is characterized by a short sleep latency and a sleep-onset REM period in approximately 50% of cases. Aside from the short sleep latency, it is also characterized by an inability to stay asleep. Patients with narcolepsy experience frequent awakenings during sleep.

Can Xyrem cause insomnia?

In the clinical trial experience with Xyrem in narcolepsy/cataplexy patients at recommended doses, two patients reported anxiety and one reported insomnia following abrupt discontinuation at the termination of the clinical trial; in the two patients with anxiety, the frequency of cataplexy had increased markedly at the …

How long does it take for Xyrem to work?

Taking the doses Some people fall asleep within 5 minutes, and most people fall asleep within about 15 minutes. That is why you need to be in bed for each dose.

How long does Xyrem stay in your system?

It is eliminated mainly by metabolism with a half-life of 0.5 to 1 hour. Pharmacokinetics are nonlinear with blood levels increasing 3.7-fold as dose is doubled from 4.5 to 9 grams (g).

Can you lose weight with narcolepsy?

Several studies have established that patients with narcolepsy tend to be overweight [5], [6], [7]. However, to date only a single report in abstract form by one of the authors (R.K.R.) has noted weight loss in patients with cataplexy after treatment [11].