How much should I load amiodarone?

How much should I load amiodarone?

How much should I load amiodarone?

2 Patients who received intravenous amiodarone for one to three weeks should take 600 to 800 oral amiodarone per day, and patients who received intravenous amiodarone for more than three weeks should take 400 mg oral amiodarone per day.

How many times can you bolus amiodarone?

Pediatric advanced life support dosing is 5 mg/kg (maximum 300 mg per dose) rapid bolus IV/IO for cardiac arrest. This dose may be repeated two times if VF or pulseless VT persists.

Is 400 mg of amiodarone too much?

Amiodarone Dosage The recommended starting dose of amiodarone is 800 to 1,600 mg/day for 1 to 3 weeks. When adequate arrhythmia control is achieved, or if you have side effects, the amiodarone dose should be reduced to 600 to 800 mg/day for one month and then to the maintenance dose, usually 400 mg/day.

When do you give amiodarone bolus?

Amiodarone can cause severe irritation of the vein, therefore adequate rinsing after bolus injection must be ensured. In treatment of prolonged, refractory ventricular fibrillation, after administration of adrenaline and defibrillation, 300 mg as bolus injection and repeated, if necessary, with 150 mg bolus injection.

How do I use amiodarone to load?


  1. Load: 800-1600 mg PO qDay for 1-3 weeks until response; once adequate arrhythmia control achieved, reduce dose to 600-800 mg/day for 1 mo; THEN reduce to maintenance dose.
  2. Maintenance dose: 400 mg PO qDay.

Can you IV push amiodarone?

When administering amiodarone peripherally via IV push, follow peripheral injection of resuscitation drugs with a bolus injection of 10 to 20 mL IV fluid. Elevate the extremity for 10 to 20 seconds following peripheral injection to facilitate drug delivery to the central circulation.

Can amiodarone be mixed with normal saline?

Amiodarone is incompatible with saline and should be administered solely in 5% dextrose solution.

How long does it take to load amiodarone?


Loading infusions 150 mg over the FIRST 10 minutes (15 mg/min).
Maintenance infusion 540 mg over the REMAINING 18 hours (0.5 mg/min). Decrease the rate of the slow loading infusion to 0.5 mg/min.

How do you give amiodarone bolus?

Use of a 0.2 or 0.22 micron filter is recommended for intermittent and continuous infusions.

  1. Bolus doses: in 100 ml D5W over 10 min (maximum infusion rate 30 mg/min)
  2. Continuous infusion: in 500 ml D5W (in non PVC bag) over 24 hours.
  3. Cardiac Arrest: First dose: Give 300 mg (6 mL) IV direct UNDILUTED.