How many years can you take Valtrex?

How many years can you take Valtrex?

Valacyclovir enhances acyclovir bioavailability compared with orally administered acyclovir. Long-term use of acyclovir for up to 10 years for HSV suppression is effective and well tolerated.

Is it safe to take valacyclovir long term?

Taken long term, particularly in people with existing kidney issues and/or inadequate hydration, valacyclovir can lead to renal toxicity and kidney failure. It can also lead to inflammation of the liver in certain people, particularly those with existing liver health issues.

How long can you take Valtrex for herpes?

The recommended dosage of VALTREX for treatment of initial genital herpes is 1 gram twice daily for 10 days. Therapy was most effective when administered within 48 hours of the onset of signs and symptoms. The recommended dosage of VALTREX for treatment of recurrent genital herpes is 500 mg twice daily for 3 days.

Can herpes become resistant to valacyclovir?

Acyclovir resistance is not common but does occur at higher rates in immunocompromised patients. Acyclovir resistance can be attributed to thymidine kinase mutations and confers cross-resistance among the antiviral nucleoside analogs (acyclovir, valacyclovir, famciclovir, and penciclovir).

Can you become resistant to Valtrex?

Resistance usually develops due to mutations in the thymidine kinase pathway that cause patients to become non-sensitive to acyclovir and its pro-drug valacyclovir, according to Dr. Thimons.

Does Valtrex affect immune system?

However, because they suppress the immune system, these medicines also suppress the ability of the body to fight infection. Valaciclovir is therefore given to people who have received an organ transplant, in order to help the body kill off any CMV virus.

Is Valtrex hard on your kidneys?

Valtrex can be harmful to the kidneys, and these effects are increased when it is used together with other medicines that can harm the kidneys. Tell your doctor about all other medications you are using. You may need dose adjustments or special tests when taking certain medications together with Valtrex.

Can I get acyclovir over the counter?

Acyclovir is a prescription medication and, as a result, acyclovir OTC is not available in the US. As a result, one cannot simply buy acyclovir online. Instead, one needs a prescription from a medical provider first.