What is fongs disease?

What is fongs disease?

What is fongs disease?

Comment. Fong disease, also known as hereditary onycho-osteodystrophy (HOOD) and commonly known as nail-patella syndrome (NPS), is a rare autosomal dominant hereditary disorder. Its incidence is approximately 1 in 50,000 new-borns.

Is there an artificial patella?

The artificial kneecap has been implanted, providing relief from the bone-on-bone scraping and allowing the knee to move more fluidly with substantial pain reduction.

Is there such a thing as nail patella syndrome?

The name “nail–patella” can be very misleading because the syndrome often affects many other areas of the body, including even the production of certain proteins. Those affected by NPS may have one or more affected areas of the body, and its severity varies depending on the individual.

What does patella syndrome do to your body?

From Wikipedia, the free encyclopedia Nail–patella syndrome is a genetic disorder that results in small, poorly developed nails and kneecaps, but can also affect many other areas of the body, such as the elbows, chest, and hips.

Is the LMX1B gene responsible for nail patella syndrome?

In rare cases, people who have symptoms of nail-patella syndrome do not have a pathogenic variant in the LMX1B gene. Therefore it is thought that there may be other genes in which pathogenic variants cause nail-patella syndrome. [3] Nail-patella syndrome is inherited in an autosomal dominant manner. [1]

How many people have patellar aplasia in the world?

The skeletal structures of individuals who have this disorder may have pronounced deformities. As reported by several medical doctors, the following features are commonly found in people who suffer from nail–patella syndrome: Patellar involvement is present in approximately 90% of patients; however, patellar aplasia occurs in only 20%.

What kind of diseases do people with nail patella syndrome have?

People with nail-patella syndrome are at a higher risk to develop increased pressure in the eye (glaucoma). About 30-50% of people with nail-patella syndrome have kidney disease. The most common feature of kidney disease is having high levels of protein in the urine (proteinuria).

What kind of horns do people with nail patella syndrome have?

Iliac horns are very common in people with nail-patella syndrome and are rarely, if ever, seen in people without this condition. Other areas of the body may also be affected in nail-patella syndrome, particularly the eyes and kidneys.

Is there a genetic test for nail patella syndrome?

Nail-patella syndrome is diagnosed based on the signs and symptoms present (this is called a “clinical diagnosis” and means that laboratory or genetic testing is not necessary for the diagnosis).

What is the prognosis for nail patella syndrome?

Prognosis. While many people with nail-patella syndrome do not have serious medical problems, many people have medical complications, including frequent kneecap dislocations , the development of early-onset arthritis, glaucoma, or kidney problems. About 5% of people with nail-patella syndrome develop end-stage kidney…