Can hydralazine cause rebound hypertension?

Can hydralazine cause rebound hypertension?

Can hydralazine cause rebound hypertension?

Possible serious side effects include: Severe rebound high blood pressure. Severe low blood pressure. Slow heart rate.

How long does rebound blood pressure last?

BB rebound may occur in a period between 1 day and even 2 weeks following discontinuation [8]. Early studies have shown that the BB withdrawal response continues for a minimum of 1 week, and that discontinuation needs to be done gradually over several weeks [26].

Which blood pressure medications cause rebound hypertension?

α-Adrenergic Receptor Antagonists It is known that abrupt discontinuation of many antihypertensive drugs can cause rebound hypertension (Houston, 1981). Drugs that act on the sympathetic nervous system, clonidine, α-methyldopa, and β-adrenergic receptor antagonists clearly have this effect.

What causes rebound hypertension?

Rebound hypertension occurs when blood pressure rises after you stop taking or lower the dose of a drug (typically a medicine to lower high blood pressure). This is common for medicines that block the sympathetic nervous system like beta blockers and clonidine.

How is rebound hypertension treated?

Treatment recommendations for rebound hypertension and acute withdrawal after sudden cessation of oral or parenteral clonidine therapy include aggressive treatment of severe hypertension by intravenous bolus injection of phentolamine and reinstitution of oral clonidine therapy (0.1–0.2 mg followed by 0.1 mg hourly as …

What happens if you abruptly stop taking blood pressure medication?

Abruptly stopping any medication used to treat high blood pressure could be very dangerous. Your blood pressure may rise, putting you at risk for a heart attack, stroke, and other life-threatening conditions.

How do you control rebound hypertension?

How long does rebound tachycardia last?

The rebound maximum, 2 days after drug withdrawal, and the 6-day duration correspond well with studies in hypertensive patients, where the transient hypersensitivity to isoproterenol or exercise-induced tachycardia commenced 2 to 6 days after cessation and lasted for 3 to 13 days (Nattel et al., 1979).