How does the influenza virus enter the host cell?
How does the influenza virus enter the host cell?
How does the influenza virus enter the host cell?
The first step of influenza virus entry is the recognition of the host cell receptor molecule, terminal α-sialic acid, by HA. This multivalent attachment by multiple copies of trimetric HA triggers endocytosis of influenza virus that is contained in the endosome. The endosome-trapped virus traffics via a unidirectional pathway to near the nucleus.
How does a virus get into the respiratory system?
Viral respiratory infections result when a virus infects the cells of the respiratory mucosa; this can occur when virus particles are inhaled or directly contact a mucosal surface of the nose or eyes. Infected individuals shed virus into the environment by coughing or sneezing or even during quiet breathing.
How is the flu infecting Your Body?
Flu symptoms are caused by your body’s immune response. The flu vaccine is your best line of defense against the virus. Along with colorful leaves, cozy sweaters, pumpkin spice lattes and all the things that make fall great is something predictable yet decidedly less fun: the seasonal flu.
How are viruses spread in the human body?
“Viruses can’t live alone, they come into the body and circulate in the blood looking to migrate into human cells where they can replicate and grow and increase in numbers. “As the virus goes on to multiply inside your body you can get symptoms of an infection.”
Where does the influenza virus attach to cells?
As with other viruses, the influenza virus must attach to specific proteins called receptors on the outside of cells in order to gain entry into cells and cause an infection. Unlike human influenza viruses, which infect cells high in the respiratory tract, the H5N1 HA protein attaches to cells much lower in the respiratory track.
How does the influenza virus affect the human body?
The influenza viruses are some of the most important human pathogens, causing substantial seasonal and pandemic morbidity and mortality. In humans, infection of the lower respiratory tract of can result in flooding of the alveolar compartment, development of acute respiratory distress syndrome and d …
How does the flu spread from person to person?
Flu, or influenza, is a contagious respiratory illness that spreads from person to person through the air via coughs or sneezes or through contact with infected surfaces. It is caused by a group of continuously changing viruses called influenza viruses.
Viral respiratory infections result when a virus infects the cells of the respiratory mucosa; this can occur when virus particles are inhaled or directly contact a mucosal surface of the nose or eyes. Infected individuals shed virus into the environment by coughing or sneezing or even during quiet breathing.